| Friday, January 1st, 2010 |
| Drafted LF J. Burkett in the 2010 inaugural draft (Round 1, Pick 26, 26th overall Pick). |
| Drafted CF T. Cobb in the 2010 inaugural draft (Round 2, Pick 5, 35th overall Pick). |
| Drafted 1B H. Zimmerman in the 2010 inaugural draft (Round 3, Pick 26, 86th overall Pick). |
| Drafted SP B. Gibson in the 2010 inaugural draft (Round 4, Pick 5, 95th overall Pick). |
| Drafted SP T. Keefe in the 2010 inaugural draft (Round 5, Pick 26, 146th overall Pick). |
| Drafted C B. MacKey in the 2010 inaugural draft (Round 6, Pick 5, 155th overall Pick). |
| Drafted SP D. Davenport in the 2010 inaugural draft (Round 7, Pick 26, 206th overall Pick). |
| Drafted SS H. Wagner in the 2010 inaugural draft (Round 8, Pick 5, 215th overall Pick). |
| Drafted MR H. Vaughn in the 2010 inaugural draft (Round 9, Pick 26, 266th overall Pick). |
| Drafted 3B B. Horner in the 2010 inaugural draft (Round 10, Pick 5, 275th overall Pick). |
| Drafted 2B C. Childs in the 2010 inaugural draft (Round 11, Pick 26, 326th overall Pick). |
| Drafted SP C. Buffinton in the 2010 inaugural draft (Round 12, Pick 5, 335th overall Pick). |
| Drafted SP S. Coveleski in the 2010 inaugural draft (Round 13, Pick 26, 386th overall Pick). |
| Drafted RF L. O'Doul in the 2010 inaugural draft (Round 14, Pick 5, 395th overall Pick). |
| Drafted MR B. Taylor in the 2010 inaugural draft (Round 15, Pick 26, 446th overall Pick). |
| Drafted MR D. Redding in the 2010 inaugural draft (Round 16, Pick 5, 455th overall Pick). |
| Drafted MR G. Brunet in the 2010 inaugural draft (Round 17, Pick 26, 506th overall Pick). |
| Drafted MR S. Sallee in the 2010 inaugural draft (Round 18, Pick 5, 515th overall Pick). |
| Drafted C C. Bolton in the 2010 inaugural draft (Round 19, Pick 26, 566th overall Pick). |
| Drafted RF G. Gore in the 2010 inaugural draft (Round 20, Pick 5, 575th overall Pick). |
| Drafted SS J. Reilly in the 2010 inaugural draft (Round 21, Pick 26, 626th overall Pick). |
| Drafted CF L. Mazzilli in the 2010 inaugural draft (Round 22, Pick 5, 635th overall Pick). |
| Drafted LF M. Rettenmund in the 2010 inaugural draft (Round 23, Pick 26, 686th overall Pick). |
| Drafted RF B. McGowan in the 2010 inaugural draft (Round 24, Pick 5, 695th overall Pick). |
| Drafted 2B R. Youngs in the 2010 inaugural draft (Round 25, Pick 26, 746th overall Pick). |
| Drafted 3B B. Werber in the 2010 inaugural draft (Round 26, Pick 5, 755th overall Pick). |
| Drafted CF E. Roush in the 2010 inaugural draft (Round 27, Pick 26, 806th overall Pick). |
| Drafted 1B J. Anderson in the 2010 inaugural draft (Round 28, Pick 5, 815th overall Pick). |
| Drafted SP L. Cheney in the 2010 inaugural draft (Round 29, Pick 26, 866th overall Pick). |
| Drafted SP W. Spahn in the 2010 inaugural draft (Round 30, Pick 5, 875th overall Pick). |
| Drafted 2B F. Thompson in the 2010 inaugural draft (Round 31, Pick 26, 926th overall Pick). |
| Drafted C A. Spohrer in the 2010 inaugural draft (Round 32, Pick 5, 935th overall Pick). |
| Drafted LF S. Crawford in the 2010 inaugural draft (Round 33, Pick 26, 986th overall Pick). |
| Drafted SP M. Mussina in the 2010 inaugural draft (Round 34, Pick 5, 995th overall Pick). |
| Drafted CL J. Mesa in the 2010 inaugural draft (Round 35, Pick 26, 1046th overall Pick). |
| Drafted SS M. Wills in the 2010 inaugural draft (Round 36, Pick 5, 1055th overall Pick). |
| Drafted CL M. Clear in the 2010 inaugural draft (Round 37, Pick 26, 1106th overall Pick). |
| Drafted CL R. Reed in the 2010 inaugural draft (Round 38, Pick 5, 1115th overall Pick). |
| Drafted 3B D. Prothro in the 2010 inaugural draft (Round 39, Pick 26, 1166th overall Pick). |
| Drafted LF J. Cardenal in the 2010 inaugural draft (Round 40, Pick 5, 1175th overall Pick). |
